Hotel Republic San Diego, Autograph Collection

About

HOTEL OVERVIEW Hotel Republic San Diego, Autograph Collection is a modern lifestyle hotel in downtown San Diego, designed for business and leisure travelers who want style, comfort, and personalized service. Located in the heart of the Civic Zone and steps from the Gaslamp Quarter, Little Italy, and the Convention Center, our boutique hotel captures the energy of the city while offering a warm, welcoming retreat. GUEST ROOMS & SUITES Our guest rooms and suites feature a bright, coastal-inspired design with plush bedding, 49" HDTVs, mini-refrigerators, coffee makers, and spacious work areas. Many rooms are filled with natural light, some with built-in window seats for added comfort, and others with expansive city views. With modern bathrooms, high-speed Wi-Fi, and thoughtful amenities, our accommodations blend California style with the convenience today’s traveler expects. Whether staying for business, a weekend getaway, or an extended trip, our rooms balance relaxation with productivity. MEETINGS & EVENTS With nearly 16,000 square feet of flexible indoor and outdoor event space, Hotel Republic is one of the top San Diego meeting and event hotels. Meeting rooms feature in-house advanced technology, abundant natural light, and open layouts with no columns or obstructions. Perfect for conferences, corporate meetings, weddings, and social celebrations, our venues combine style with functionality. Dedicated event planning services and spectacular catering ensure every gathering runs seamlessly. DINING & SOCIAL SPACES Our social atmosphere comes alive with handcrafted cocktails at the lobby bar, locally inspired dining at Trade Restaurant, and skyline views at Topside Terrace Kitchen & Bar, one of San Diego’s favorite rooftop venues. From happy hours and wine tastings to fireside conversations, Hotel Republic is the social hub of downtown. LOCATION & ACCESSIBILITY Hotel Republic San Diego places you in the center of it all. Our downtown location puts guests within walking distance of the Gaslamp Quarter, Little Italy, and San Diego’s vibrant waterfront. The San Diego Convention Center and Petco Park are minutes away, making the hotel a perfect choice for meetings, conferences, and corporate events. We are just a short drive from San Diego International Airport, Balboa Park, and the world-famous San Diego Zoo. Guests can explore the Embarcadero, Seaport Village, and USS Midway Museum, all within easy reach. For dining and nightlife, the city’s best restaurants, breweries, and rooftop lounges surround the hotel, while quick freeway access makes it simple to reach La Jolla, Coronado Island, and other Southern California attractions.

Meeting space

Meeting space
Industry 3 & 4111802.7432000000000003 m
Industry 2 & 31351002.7432000000000003 m
Industry 1-42412002.7432000000000003 m
Studio 238322.86512 m
Industry 1-31901502.7432000000000003 m
Studio 1 & 275602.86512 m
Grand1771603.4747200000000005 m
Industry 360402.7432000000000003 m
Industry 453402.7432000000000003 m
Salon Patio2035—
Salon47553.6576000000000004 m
Industry 2-41861402.7432000000000003 m
Industry 155402.7432000000000003 m
Great Room1541502.86512 m
Industry 1 & 21311002.7432000000000003 m
Topside East112100—
Topside229200—
Industry 276602.7432000000000003 m
Veranda Club & Deck15050—
Great Room & Studios2302002.86512 m
Topside West110100—
Veranda Deck7376—
Grand Patio8940—
Studio 137322.86512 m
Veranda Club76303.1394400000000005 m

Facilities

Facilities
Food and drink
Business, internet and AV
Event equipment
Parking
Getting there
Guest rooms and services
Leisure

Getting there

421 West B Street

Nearby venues